Subependymal heterotopia / Periventricular Nodular Heterotopia (PVNH)

Subependymal heterotopia Radiology

Subependymal heterotopia/Periventricular Nodular Heterotopia

  • Arrest of normal neuronal migration along the radial glial cells.
  • Subependymal nodules of grey matter line the lateral walls of the ventricles.
  • Nodules follow grey matter signal intensity and do not enhance following contrast administration.
  • Associations:
    • Ventriculomegaly.
    • Agenesis of corpus callosum.
    • Cortical dysplasia
  • Differential
    • Tuberous sclerosis: Subependymal nodules in TS are often calcified and other associated features are present.

Case Courtesy
BK Diagnostic Center

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