Subependymal heterotopia / Periventricular Nodular Heterotopia (PVNH)

Subependymal heterotopia/Periventricular Nodular Heterotopia

• Arrest of normal neuronal migration along the radial glial cells.
• Subependymal nodules of grey matter line the lateral walls of the ventricles.
• Nodules follow grey matter signal intensity and do not enhance following contrast administration.
• Associations:
  • Ventriculomegaly.
  • Agenesis of corpus callosum.
  • Cortical dysplasia
• Differential
  • Tuberous sclerosis: Subependymal nodules in TS are often calcified and other associated features are present.

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