What causes scalloped vertebrae in the spine on imaging?
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Answer:
Posterior scalloping of vertebral bodies is caused by dural ectasia, neurofibromatosis type 1 (NF1), or mucopolysaccharidoses, resulting in erosion of the posterior vertebral margins due to abnormal dural expansion or dysplastic bone remodeling.
Why is it called so?:
Scalloped vertebrae refers to the smooth, concave erosion of the posterior vertebral body margins resembling the scalloped edges of a shell or pie crust.
Pathophysiology:
Dural ectasia leads to focal dilation of the dural sac, exerting chronic pressure on adjacent bone causing posterior vertebral body scalloping; in NF1, this combines with mesodermal dysplasia and neurofibromas contributing to anterior/lateral scalloping, while mucopolysaccharidoses cause dysostosis multiplex with similar erosive changes.
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